Trimethylamine (TMA)
Amines

Trimethylamine (TMA)

Trimethylamine (TMA), identified by CAS Registry Number 75-50-3, is a fundamental tertiary amine with the molecular formula $(CH_3)_3N$. It is the simplest member of the tertiary amine family, consisting of a central nitrogen atom covalently bonded to three methyl groups. At standard temperature and pressure, TMA is a colorless, highly flammable gas characterized by a distinctive “fishy” odor at low concentrations, which transitions to a pungent, ammonia-like scent at higher concentrations.

Industrially, TMA is synthesized through the vapor-phase catalytic reaction of methanol and ammonia. Due to its low boiling point of 2.9°C, it is commercially distributed either as a pressurized liquefied gas or as an aqueous solution (typically 25% to 40% concentration). As a versatile nucleophile, TMA serves as a critical building block in the chemical industry, particularly for the synthesis of choline salts, quaternary ammonium compounds, and ion exchange resins. Its absence of N-H bonds makes it chemically stable under conditions where primary or secondary amines would undergo acetylation or similar substitutions.

Attributes

Key Features and Benefits

* Serves as a versatile chemical intermediate for numerous synthetic processes.
* Crucial raw material for agricultural applications, including pesticides and choline chloride.
* Indispensable in the synthesis of pharmaceuticals and effective disinfectants.
* Key component in the production of ion exchange resins and various surfactants.
* Acts as an accelerator in rubber vulcanization and an auxiliary in textile processing.
* Supports the manufacturing of dyestuffs and specialized flotation agents.
* Provided as a stable 40% aqueous solution, ensuring ease of handling and integration.
* Offers consistent quality, suitable for a broad spectrum of demanding industrial uses.

Specifications

Technical Highlights

* Trimethylamine (Aqueous): Min. 30.0 %wt
* Trimethylamine (Anhydrous): Min. 99.0 %wt
* Dimethylamine: Max. 100 ppm
* Monomethylamine: Max. 10 ppm
* Water (Aqueous): Max. 70.0 %wt
* Water (Anhydrous): Max. 0.05 %wt
* Appearance: Clear colorless liquid
* Specific Gravity @ 20°C (Aqueous): 0.945 – 0.955
* Freezing Point (Aqueous): -15.0 approx °C
* Boiling Point (Anhydrous): 3.0 °C

Download Technical Data Sheet (TDS)

Practical industry uses

Applications

* **Chemical Synthesis:** Serves as a versatile chemical intermediate and building block for synthesizing a wide range of organic compounds and quaternary ammonium compounds.
* **Pharmaceuticals:** Crucial for the synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs) in the drug manufacturing process.
* **Agriculture:** Utilized in the production of various agrochemicals, including pesticides, herbicides, fungicides, and plant growth regulators.
* **Water Treatment:** Acts as an effective scavenger for oxygen and carbon dioxide in boiler water systems and as a component in corrosion inhibitors.
* **Rubber Industry:** Functions as an accelerator in the vulcanization process, significantly speeding up the curing of rubber.
* **Textile Industry:** Employed in the manufacturing of dyes and various textile auxiliaries used for fabric processing and finishing.

Key Sectors

Target Industries

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