High-Purity Solvents, Personal Care

Vitamin E Acetate 98%

Vitamin E Acetate (CAS No. 7695-91-2), chemically known as DL-alpha-tocopheryl acetate, is the stable esterified form of alpha-tocopherol. While natural tocopherols are highly sensitive to oxidation, heat, and light, the acetylation of the phenolic hydroxyl group in this compound provides significantly enhanced stability, making it the preferred choice for industrial formulations. This 98% high-purity grade presents as a viscous, clear, pale-yellow oily liquid that is practically odorless.

Biologically, Vitamin E Acetate acts as a pro-vitamin; upon topical application or ingestion, it is hydrolyzed by esterase enzymes into free tocopherol, which then exerts its potent antioxidant properties. It functions as a chain-breaking antioxidant, protecting polyunsaturated fatty acids within cellular membranes from lipid peroxidation. Due to its chemical robustness and biological efficacy, it is a primary ingredient in the pharmaceutical, nutraceutical, and personal care sectors. It serves as a critical fat-soluble micronutrient, essential for maintaining cellular integrity and protecting tissues from oxidative stress induced by environmental factors.

Attributes

Key Features and Benefits

Superior Oxidative Stability: Unlike free tocopherol, the acetate form is highly resistant to atmospheric oxygen and light, ensuring a long shelf-life in finished products.
Thermal Resilience: Maintains structural integrity during high-temperature manufacturing processes, such as emulsification or extrusion.
Biological Potency: Readily converted to active alpha-tocopherol by cellular esterases, providing effective free-radical scavenging.
Dermal Benefits: Acts as a moisturizing agent and improves skin elasticity while providing protection against UV-induced photo-aging.
High Purity Grade: The 98% concentration ensures minimal impurities, meeting rigorous USP/EP/BP pharmacopeia standards for safety and efficacy.
Synergistic Effects: Works effectively in combination with Vitamin C (Ascorbic Acid) to regenerate antioxidant capacity within lipid and aqueous phases.

Specifications

Technical Highlights

Chemical Formula: $C_{31}H_{52}O_{3}$
Molecular Weight: 472.74 g/mol
Assay (Purity): $ge$ 98.0% DL-alpha-tocopheryl acetate.
Physical State: Clear, colorless to slightly greenish-yellow, viscous oily liquid.
Solubility: Practically insoluble in water; freely soluble in ethanol, acetone, chloroform, and vegetable oils.
Refractive Index: 1.494 – 1.498 at 20°C.
Specific Gravity: 0.952 – 0.966 g/cm³ at 25°C.
Optical Rotation: Optically inactive (racemic mixture).
Acidity: $le$ 1.0 mL of 0.1N NaOH required for neutralization per 1.0g sample.
Storage Conditions: Store in airtight containers, protected from light, at controlled room temperature.

Download Technical Data Sheet (TDS)

Practical industry uses

Applications

Cosmetic Formulations: Widely utilized in anti-aging creams, sunscreens, lipsticks, and lotions for skin conditioning and antioxidant protection.
Nutraceutical Supplements: A primary source of Vitamin E in softgel capsules, tablets, and multi-vitamin complexes for immune support.
Food and Beverage Fortification: Used to enrich fats, oils, and cereal-based products where long-term stability is required.
Pharmaceutical Preparations: Employed as an active pharmaceutical ingredient (API) in topical ointments for wound healing and dermatological disorders.
Animal Nutrition: Included in high-grade feed premixes to improve livestock health and the oxidative stability of animal-derived products.
Safety Warning: Strictly prohibited for use in inhalation or vaping products due to the risk of E-cigarette or Vaping Use-Associated Lung Injury (EVALI).